October Case of the Month Clinical History: A 70-year-old man with an apparently isolated lower lobe lung mass underwent CT-guided core needle biopsy. On H&E sections (Figure 1: 40x, Figure 2: 200x, Figure 3: 400x) there are up to 4 mitotic figures per 3 high-power fields. The neoplasm has patchy reactivity with antibodies directed against EMA (Figure 4) and progesterone receptor (Figure 5), and diffuse strong reactivity with antibodies directed against SSTR2A (Figure 6). There is no reactivity with antibodies directed against AE1/AE3, TTF-1, napsin A, p40, synaptophysin, SOX10, S100, STAT6 or CD34..

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