Save the Date!
June 23-25, 2021
2021 PPS Biennial Meeting

In collaboration with Association of Pulmonary Pathologists (APP)

Victor Roggli, MD
2020 PPS Lifetime Achievement Award

June Case of the Month

Clinical History: Middle aged man with a large central lung tumor. Endobronchial biopsies demonstrate a poorly differentiated high grade neoplasm with abundant necrosis (Figures 1-2). The tumor is composed of round to oval discohesive cells with prominent nucleoli, abundant mitotic activity and a relatively monomorphic appearance (Figures 3-5). Numerous rhabdoid cells with distinctive eosinophilic cytoplasmic inclusions indenting eccentrically located nuclei are present (Figures 3-5). The neoplastic cells are negative for all cytokeratins including, 7, 5/6, AE1/AE3, OSCAR and cam 5.2. The cells are negative for neuroendocrine markers synaptophysin, chromogranin, and CD56. The cells are also negative for CD45, TTF-1, p40, NUT, SOX10, CD31 and desmin. The cells have intact expression of INI-1. The neoplastic cells demonstrate complete loss of BRG1 expression (Figure 6).

Click here to see more.










Renew or Apply On Line
Pulmonary Pathology
Journal Club
April (pdf) (mp3)
May (pdf) (mp3)
Journal Club Archive
Upcoming Meetings

June 18-24, 2020
Graz, Austria
Postgraduate Course
Lung & Pleural Diseases

Faculty:
Helmut H. Popper
Junya Fukuoka
Luka Brcic
Ulrike Gruber-Moesenbacher

Flyer:
Course website
email:

 


facebook  twitter ...
2020 PPS Lifetime Achievement Award
Professor Victor Roggli
Copyright © 2019, PPS, all rights reserved.
For questions or comments, please contact webmaster@pulmonarypath.org