May Case of the Month Clinical History: A 73-year-old woman with prior history of invasive ductal breast carcinoma status-post surgical resection, radiation, and endocrine therapy presented to her physician with lingering cough after COVID-19 infection. A CT scan detected a 1.8 cm indeterminate nodule in the left upper lobe with relatively smooth margins. PET/CT scan showed that the nodule was hypermetabolic with FDG avidity similar to that of the liver, suspicious for metastatic disease. The patient underwent a core biopsy of the nodule (not shown) and later left upper lobectomy. Histologic sections of the nodule are shown in Figures 1 through 6. A Fontana-Masson stain is shown in Figure 5.

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